Pfizer Senior Scientist in Pearl River, New York
The candidate will develop analytical assays and design, plan and execute the qualification and transfer of these assays in support of Vaccine development, including materials release and stability for early phase vaccine programs. The focus of this position is for assay development for nucleic acid and nucleic acid lipid delivery platform formulations utilizing standard analytical techniques such as HPLC, CE, UV-Vis, Mass Spectrometry and other applicable techniques.
The individual should be able to identify key Vaccine drug substance and drug product attributes and provide hands on support to develop robust assays for routine use with a focus on nucleic acid vaccines
The individual should be familiar with basic regulatory expectations and the ICH guidelines for method qualification
Contribute to the selection of the methodology and techniques to be used
Independently analyze, interpret, provide conclusions and present experimental data internally
Perform routine sample analysis
Independently design, plan, and execute assay development, qualification and transfer studies to support the release, stability and characterization of vaccine candidates
Collaborate with colleagues within Vaccine Research and Development - Bioprocess, Analytical, and Formulation Development and appropriate partner lines
Author and review laboratory methods and reports
Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review
As needed, introduce and utilize new technologies and establish those technologies to characterize the vaccines under development Where applicable, perform job responsibilities in compliance with GLP and all other regulatory agency requirements
PhD in Chemistry, Biochemistry, or related discipline with at least 2 years of academic, pharmaceutical, or biotechnology postdoctoral experience or an MS plus 7 years of related work experience is required.
Experience in analytical assay development for nucleic acid and nucleic acid lipid delivery platform is essential.
A strong background in separation-based analytical techniques and method qualification using ICH guidelines is essential. Experience with applying these methodologies to biomolecules, such as nucleic acid is preferred. Proficiency and ability to utilize techniques such as HPLC, CE, and UV-Vis to develop methods to analyze potential vaccine antigens and other vaccine components.
Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable. Strong verbal and written communication skills are required.
EEO & Employment Eligibility
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Other Job Details:
Eligible for Relocation Package
Eligible for Employee Referral Bonus
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.