Pfizer Senior Scientist, Microbial Genomics in Pearl River, New York
Senior Scientist, Microbial Genomics
We are looking for a highly motivated microbiologist in the field of microbial genomics. The successful applicant should have an understanding of next-generation sequencing technology and be proficient in NGS analysis. A deep understanding of microbiome biology, as well as experience with both 16S rRNA and metagenomic NGS is preferred. In addition, the applicant should have a strong understanding of microbial physiology and processes.
The successful candidate will have a unique opportunity to work with a multidisciplinary team on a wide range of microbial genomic, epidemiologic, and microbiome research projects. Excellent communication skills and the ability to work a multifunctional matrix environment are essential for the success of this candidate. This is an exciting opportunity for candidates with strong data driven skills and who want to work in a strong collaborative environment and will be expected to conduct experiments in the wet lab, and manage laboratory and data analysis responsibilities to achieve team goals.
Responsibilities include but not limited to:
Apply phenotypic and molecular tests to whole genome sequence data such as the functional impact of protein mutations. Use NGS or deep sequencing technologies to examine gut microbiota in animal and human samples in order to understand microbiome changes during disease and from drug treatment intervention. Lead the interpretation of microbial population structure and functional signatures from clinical and translational studies. Electronic documentation of lab work in a detailed fashion, summarizing and reporting data in an organized fashion. Stay current in microbial genomics research tools and emerging approaches in microbiome genomics by keeping up with relevant literature and attending scientific meetings. Prepare results for presentation, inclusion in technical reports, and for publication in peer-reviewed scientific journals.
Advanced scientific degree (PhD) in Microbiology, Molecular biology or Genomics with minimum of two years of relevant post-graduate experience and demonstrated data analysis and strong publication record.
The qualified applicant must have a background in microbiology or related field with experience in complex microbiome research - preferably gut microbiome.
Experience in microbiological techniques such as culturing aerobic, microaerophilic, and anaerobic bacterial pathogens and commensals.
Experience in nucleic acid isolation, RT/PCR, NGS library preparation including RNAseq, 16S rRNA, shotgun metagenomics.
Competence in NGS analysis tools including genome assembly, annotation, and comparative genomics.
Ability to effectively manage, organize and prioritize multiple projects and meet deadlines.
Excellent critical thinking, communication and organizational skills.
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