Pfizer Sr. Manager, Clinical Pharmacology in La Jolla, California


A clinical pharmacologist with a PhD, Pharm.D (with fellowship) or a MD degree with at least 3-5 yrs. of academic/industry experience. The candidate will be working in a team of scientists reporting to a group lead in San Francisco supporting a late stage immuno-oncology program. The candidate will be a part of the Pfizer Oncology Clin Pharm team with approximately 30 scientists. We emphasize on the candidate's quantitative pharmacology skills, scientific reasoning, regulatory affairs skills, written and verbal communication skills, exploratory graphical analysis skills, study design and report writing skills.

Under the direction of the team leader the candidate will act as the primary clinical pharmacology lead providing clinical pharmacology expertise to a multidisciplinary study team for a late-stage immuno-oncology program


  • Provide clinical pharmacology expertise to multidisciplinary study teams for a late stage immuno-oncology program.

  • Under the supervision of the ClinPharm group leader, work closely with clinicians, statisticians, translational oncology and clinical operations colleagues to design, conduct and report results of clinical trials.

  • Responsible for designing and implementing dose finding strategies to ensure optimal dose and dosing regimens in clinical trials.

  • Analyze pharmacokinetic data and integrate this knowledge into clinical trial design.

  • Draft clinical pharmacology components of protocols, clinical development plans and regulatory documents.


  • A Ph.D., Pharm.D. or equivalent training in pharmacokinetics, pharmaceutical sciences or related disciplines is required.

  • Ability to apply pharmacokinetic and pharmacokinetic-pharmacodynamic concepts, including the modeling and simulation to clinical trial design.

  • Proven record in clinical drug development with experience in oncology.

  • The ideal candidate will be an excellent communicator with strong interpersonal skills


  • Strong technical proficiency in pharmacokinetic software (e.g WinNonlin, NONMEM, S+Plus, etc.) is preferred.

  • Prior experience with large molecules and/or immuno-oncology or immunology is desirable.


Sitting, standing, walking, ability to perform mathematical calculations and ability to perform complex data analysis


Full time, exempt employee. Some limited business travel.

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Other Job Details:

  • Last Date to Apply for Job: January 31, 2019

  • Eligible for Relocation Package

  • Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.