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Pfizer Senior Associate Scientist Mammalian Protein Expression and Molecular Biology (Non in La Jolla, California

BioMedicine Design (BMD) is seeking a highly motivated scientist to join a protein expression and molecular biology group supporting the Biotherapeutics portfolio of Pfizer, Inc. in La Jolla, CA. Responsibilities will include execution on multiple steps of protein expression for biotherapeutic leads, protein reagents, immunogens, and panning reagents, as well as the design and building of DNA constructs. This includes expertise in mammalian tissue culture techniques using various cell lines and cell culture technologies. The ideal candidate will be proficient in the design of optimal processes that are consistent with team material needs for quantity (milligram to gram scale) and purity.

Job Description:

  • Perform protein expression in mammalian transient and stable cell lines, from various shake flask scales to bioreactor systems

  • Perform and/or coordinate the generation of DNA constructs tailored for the expression of recombinant proteins

  • Design, assess and troubleshoot cell culture and expression protocols.

  • Deliver cell culture supernatants and data analysis packages to project teams in a timely manner.

  • Present results regularly at team meetings

  • Perform diligent and timely notekeeping and work process tracking

Required Qualifications:

  • BA/BS in Biochemistry, Biology, or related field with 3+ years of R&D experience in an industry setting, or a Masters degree with 2+ years of industry experience

  • Experience in protein expression using transient and/or stable mammalian cell culture systems

  • Expertise in design, execution, and troubleshooting of expression processes.

  • Expertise in techniques for the monitoring of cell culture density, viability and protein titer

  • Experience with data analysis and presentation software

  • Strong written and oral communication skills

  • The ability to work closely with other group members within teams is essential

  • The individual should be scientifically creative and driven by a willingness to embrace innovation within drug discovery and an eagerness to challenge and meet aggressive timelines

Preferred Qualifications:

  • Expertise in the generation and design of plasmid constructs for expression of recombinant proteins, using cutting-edge molecular biology techniques

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Other Job Details

  • Eligible for Employee Referral Bonus


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