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Pfizer Scientist (non in La Jolla, California

Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein therapeutics to improve human life by redirecting the immune system against cancer. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics. We are seeking to hire multiple Scientists for the CID Immunosuppression group.

ROLE RESPONSIBILITIES

  • Evaluation of novel mechanisms of tumor resistance to innate and adaptive immunity

  • Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development.

  • Planning and execution of in vivo murine studies and ex vivo functional assessments, such as, multi-color flow cytometry, i mmunohistochemistry/immunofluorescence, and primary cell culture.

  • Communication of experimental results to team.

BASIC QUALIFICATIONS

  • B.S. degree with 6+ years' experience or MS (preferred) with 5+ years of experience

  • Experience in the fields of immunology, cell biology and/or genetics.

  • Ability to plan and execute and in vitro experiments with minimal supervision

  • Expertise in standard immunologic techniques

  • Technical expertise with immune cell-based functional assays (e.g. activation, differentiation, proliferation, and suppression assays by using monocyte/ macrophages, T-cells, or dendritic cells).

  • Experience with human PBMC and mammalian cell culture.

  • Experience with qRT-PCR, ELISA, MSD, ELISPOT, Nano string and cytotoxic assays.

  • Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic.

PREFERRED QUALIFICATIONS

  • Immune phenotyping tumor associated immune cells from primary human tumor samples by flow cytometry.

  • Experience in CRISPR technology and lentiviral transduction.

  • Experience working with small molecules inhibitors for tumor immunotherapy.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Other Job Details:

  • Eligible for Employee Referral Bonus

N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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