Pfizer Scientist, In Vivo Pharmacology in Groton, Connecticut

The Internal Medicine Research Unit (IMRU) is committed to finding cures for metabolic disorders. Within the IMRU, the Metabolism group focuses on identifying novel therapies to improve metabolic disorders associated with Type 2 Diabetes and fatty liver disease. We are seeking a highly motivated, scientifically and technically strong in vivo research scientist with a common goal of developing drugs to combat these metabolic disorders.

Role Responsibilities

The successful candidate will organize and conduct non-human primate efficacy studies to support the IMRU portfolio. He/She will be responsible for the operations of maintaining a large non-human primate (NHP) colony to support in-vivo efficacy studies. The candidate will be responsible for maintaining animal experimental records, and for adherence to all IACUC, local and federal guidelines. Additionally, the candidate will be able to communicate and work well both within a team and across support lines.In addition, the successful candidate will assist with rodent studies, coordinate in vivo pharmacology studies, conduct mechanistic investigations using tissues, and communicate with research unit scientists. The candidate will contribute in a team environment to research projects from early target validation to late stage drug development.

Successful candidates are expected to:

  • Have knowledge, experience and skill sets in NHP handling, dosing (PO, IV, SC), blood collection, rodent (mouse and rat) handling, dosing (PO, SC, IV), blood and tissue collection

  • Perform in vivo experiments to address key mechanistic and pharmacological scientific questions such as efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis.

  • Data Analysis, interpretation, documentation of experiments and presentation of results within a multidisciplinary team environment.

  • Demonstrate understanding of different animal models of metabolic disease (NHP and rodent) and the utilization of these models for in vivo studies

  • Characterize new in vivo models (NHP and rodent) to study biologic mechanisms and support exploration of novel therapies.

  • Work efficiently and flexibly in a team environment

  • Apply scientific and technical expertise to drug discovery programs to impact the future of new drug candidate development.Ability to follow novel scientific or technological developments, and to implement them in the laboratory. Maintain a 'cutting edge' awareness of preclinical scientific, health and technical developments. Apply scientific and technical expertise to drug discovery programs.

  • Communicate and present study results in internal meetings.

Basic Qualifications:

  • BS/BA in biology or related discipline with 3+ years of NHP/in vivo experience in pharmaceutical or biotech industry.

  • Prior experience in NHP and rodent models relevant to human metabolic diseases.

  • Possess strong written/verbal communication skills and ability to effectively collaborate with scientists working in other disciplines.

Preferred Qualifications:

  • Knowledge and expertise in the field of metabolic disease

  • Prior knowledge of statistics and commonly used processing software (Graph Pad Prism, SAS)

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Other Job Details:

  • Last Date to Apply for Job: October 24, 2018 Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.