Pfizer Ligand Binding Assay Scientist in Groton, Connecticut
This position provides biomarker bioanalytical support for ligand binding lab biomarker assets. This scientist has growing knowledge of bioanalytical methodologies related to ligand binding assay (LBA) platforms and sample preparation techniques. This individual helps lead laboratory support for assay and method development, assay validation and study support using ligand binding assay techniques.
Responsible for providing Ligand Binding based analytical data for biomarker discovery and development, supporting assay method development, validation and study execution.
Responsibilities include the quantitative analysis of novel biomarkers utilizing immunoassay techniques. Successful job performance includes development, characterization, & implementation of appropriate ligand binding assay techniques and related sample isolation technology for supporting quantitation of large molecule biomarker species.
Routine use of liquid handling systems, various immunoanalytical platforms (ELISA, MSD, Erenna, Licor etc), and Watson LIMS are required. Position requires expertise in biological sample handling and preparation, and laboratory automation.
Role includes planning of laboratory activities with key stakeholders and senior leaders, understanding and influencing therapeutic area biomarker strategies to use biomarkers in scientific decision-making.
This role will participate in all phases of ECD regulatory laboratory operations including technology evaluations, the development of sample preparation, separation and detection methods, data analysis, interpretation, reporting and follow up discussions with the project teams on utilizing the data in appropriate decision making.
All colleagues in this role are responsible for maintaining regulatory compliance appropriate for clinical and preclinical study execution including all proscribed training as found in ECD SOPs and training transcripts. This includes knowledge, training and understanding of GLP/GCP guidance for execution of preclinical and clinical studies supporting Pfizer portfolio projects as applicable.
Participate in continuous improvement of scientific and regulatory processes via update/creation of SOP's, design and implementation of laboratory and study based processes, and development of best practices for bioanalytical data generation.
Responsible for QC and peer review of raw data, results, and final reports from other colleagues within the regulated group (depending on level of training). Additionally responsible for participation in internal and external audits providing required information to auditors
Proactively gathers input from colleagues, teams & management to avoid/address issues at functional level and participates on cross discipline matrix teams
Excellent oral/written communication skills
Demonstrated ability to clearly & concisely communicate bioanalytical information (including Q&A)
Understanding of "fit-for-purpose" assay development and support. Ability to effectively balance assay rigor against resource needs and study goals
M.S. degree in Biology or other related field
3 -5 years experience
Other Job Details:
This job is Pfizer Exempt US/PR Grade: 6
US/PR colleagues who are issued an Incident Final Warning (IFW) disciplinary action are not eligible to post and compete for a position for a period of 12-months from the date an IFW is issued.
Eligible for Employee Referral Bonus
Be able to conduct labwork throughout a normal business day.
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EEO & Employment Eligibility
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Research and Development