Pfizer Sr. Principal Scientist, Clinical Pathologist in Cambridge, Massachusetts


Clinical pathologist is a global role that will function to support target and candidate confidence in rationale/mechanism and confidence in safety by providing comprehensive evaluation (verbal and/or written summaries) of biomarker strategies. Opportunities exist to write clinical pathology reports and represent project team as nonclinical safety lead and representation on issue management teams and biomarker teams, as well as leading investigative/mechanistic research related to safety findings.


  • Develops and implements innovative and efficient biomarker strategies

  • Provides DSRD Biomarker representation on project teams and relevant issues management teams to provide scientific guidance on nonclinical and clinical biomarker strategies

  • Aligns across discipline lines (eg; Pathology, Immunotoxicology and General Toxicology) to provide comprehensive safety assessment and biomarker strategies

  • Supports external influence by providing representation to external academic, consortium and industry biomarker efforts, which is important to continue to develop, validate, and implement new biomarkers and promote more effective drug development

  • Involved in the design and comprehensive evaluation of the clinical pathology endpoints in efficacy and safety (exploratory and regulatory) studies

  • Clinical pathologists that have expertise (board certification) and interest in anatomic pathology may also contribute to safety/efficacy assessment by microscopic examination of tissues

  • This position offers the opportunity to actively participate in the drug discovery and development process as the primary non-clinical safety representative to project teams (DSTL)


  • DVM/VMD degree or equivalent veterinary degree is required

  • PhD, MS or other advanced graduate degree in pathology or a related field

  • 4+ years Research experience in Toxicology, Pathology or related field

  • Board certification in clinical pathology by the ACVP/ECVP or equivalent

  • Strong verbal and written communications skills are required.

  • Ability to perform complex data analysis, integrating clinical signs and anatomic pathology findings to interpret clinical pathology data.


  • Experience in clinical pathology data interpretation in toxicological pathology and/or industry setting

  • Additional board certifications in Toxicology

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Other Job Details:

  • Last Date to Apply for Job: January 25, 2019

  • Additional Location Information: Cambridge, MA; Pearl River, NY; Groton, NY.

  • Eligible for Relocation Package

  • Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.