Pfizer Senior Scientist in Cambridge, Massachusetts


The Pfizer Inflammation &Immunology (I&I) Department seeks to develop novel and first-in-class therapeutics for the treatment of inflammatory and fibrotic diseases. The successful candidate will be responsible for identifying novel targets from experimental and literature data, conducting and coordinating key confidence-in-rationale experiments around targets of interest, and driving the biology plan for portfolio or potential portfolio programs.


The successful candidate will:

  • Coordinate and personally generate decision-making data for programs. This position is approximately 60% lab based.

  • When not in the laboratory, keep current with the literature, attend and be an active participant in team settings including as a biology leader, and prepare and present crisp, concise presentations in governance meetings.

  • Be involved in self-driven novel assay development to reproduce literature data and/or as specific experimental needs arise for targets of interest

  • Interface with colleagues in other Pfizer departments such as Medicinal Chemistry and Biomedicine Design in a highly matrixed work environment to devise plans and procure resourcing for program advancement

  • Find opportunities to publish scientific data in high impact journals

  • Regularly, and without fail, record experimental data in electronic notebook form and in Pfizer databases


  • Ph.D. in Immunology, Molecular/Cell Biology, Biochemistry, or related field

  • Demonstrated expertise with the latest immunofluorescence and multi-color microscopy techniques as evidenced by recent, high impact publication(s)

  • Experience with basic molecular and cell biology techniques including RNA isolation, Taqman, and Western blotting

  • Expertise in analyzing tissue from animal models of fibrosis and human fibrotic liver specimens

  • Excellent communication skills and demonstrated ability to be successful working in team settings

  • Advanced experience with Microsoft Office programs (Word, Powerpoint, Excel) and data analysis software (Graphpad Prism)


  • Experience working with bioinformaticians in the analysis of single cell RNASeq data

  • Experience with Visiopharm and RNAScope methodologies

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Other Job Details:

  • Last Date to Apply for Job: February 1, 2019

  • This position will be located at the Cambridge, MA site location.

  • Eligible for Relocation Package

  • Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.