Pfizer Scientist Host in Cambridge, Massachusetts

ROLE SUMMARY

We are seeking a bright, motivated, and creative scientist to join a fast-paced Inflammation & Immunology team at Pfizer. The successful applicant will have experience in microbiology and molecular or cellular biology, that will be applied to complex co-culture systems. The incumbent will develop assays to interrogate cellular and molecular pathways that underly the pathophysiology of inflammatory and autoimmune disorders, including functional readouts of autophagy and host-microbial interactions. Ultimately, this role will provide relevant knowledge and technical expertise to enable therapeutic discovery efforts aimed at mucosal healing of gut and skin barriers.

ROLE RESPONSIBILITIES

  • Develop and execute in vitro human co-culture systems involving multiple cell types to elucidate mechanisms of action for potential therapeutic candidates.

  • Identify, trouble-shoot, and optimize relevant assay systems, technologies, and readouts.

  • Independently design experiments, interpret and track results.

  • Organize, summarize, and present data.

  • Work collaboratively with project teams.

BASIC QUALIFICATIONS

  • B.S. or M.S. in Microbiology, Molecular Biology, Cellular Biology, or related discipline and at least 5 years of experience in an industrial or academic setting.

  • Experience with bacterial and mammalian cell/tissue culture and running cell-based assays.

  • Experience with WB, ELISA, MSD, HTRF, or related protein-based assay systems.

  • Experience with PCR, Taqman, or other gene expression analysis.

  • Highly motivated, independent, analytical.

  • Effective oral and written communication skills, willingness to learn new skills.

  • Ability to adapt quickly to changing project needs.

PREFERRED QUALIFICATIONS

  • Experience culturing aerobic and anaerobic bacteria, and running bacterial infection assays with mammalian cells.

  • Experience with tissue processing and flow cytometry.

  • Experience harvesting, processing, and analyzing tissues from in vivo disease models.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.