Pfizer Scientist Host in Cambridge, Massachusetts
We are seeking a bright, motivated, and creative scientist to join a fast-paced Inflammation & Immunology team at Pfizer. The successful applicant will have experience in microbiology and molecular or cellular biology, that will be applied to complex co-culture systems. The incumbent will develop assays to interrogate cellular and molecular pathways that underly the pathophysiology of inflammatory and autoimmune disorders, including functional readouts of autophagy and host-microbial interactions. Ultimately, this role will provide relevant knowledge and technical expertise to enable therapeutic discovery efforts aimed at mucosal healing of gut and skin barriers.
Develop and execute in vitro human co-culture systems involving multiple cell types to elucidate mechanisms of action for potential therapeutic candidates.
Identify, trouble-shoot, and optimize relevant assay systems, technologies, and readouts.
Independently design experiments, interpret and track results.
Organize, summarize, and present data.
Work collaboratively with project teams.
B.S. or M.S. in Microbiology, Molecular Biology, Cellular Biology, or related discipline and at least 5 years of experience in an industrial or academic setting.
Experience with bacterial and mammalian cell/tissue culture and running cell-based assays.
Experience with WB, ELISA, MSD, HTRF, or related protein-based assay systems.
Experience with PCR, Taqman, or other gene expression analysis.
Highly motivated, independent, analytical.
Effective oral and written communication skills, willingness to learn new skills.
Ability to adapt quickly to changing project needs.
Experience culturing aerobic and anaerobic bacteria, and running bacterial infection assays with mammalian cells.
Experience with tissue processing and flow cytometry.
Experience harvesting, processing, and analyzing tissues from in vivo disease models.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.