Pfizer Technical Associate, Clinical Manufacturing, Downstream in Andover, Massachusetts


  • The Technical Operations II, Clinical Manufacturing associate is part of a multi-disciplinary team responsible for cGMP production of Phase I/II clinical drug substance supporting the Pfizer Biotherapeutics portfolio.

  • Initial focus is on the start-up of a new facility in support of suite/equipment commissioning and qualification, creation of necessary cGMP documentation, and training within the production operation area.

  • Post facility start up, the successful candidate will remain on 1st shift. The successful candidate will be a part of a dynamic team responsible for the execution of downstream mammalian and microbial processes.


  • Execute downstream mammalian and microbial purification processes in a cGMP environment. Includes CIP and SIP operations.

  • Execute product change over activities with the guidance of process engineer and tech transfer team.

  • Execution of SOP's and batch record documentation of downstream unit operations.

  • Cross-functional communication with tech transfer team, quality and engineering as necessary.

  • Cross-shift communication with 2nd shift. Actively participates in shift exchange activities and communication channels.

  • Active participant of the OWN IT culture. Identifies and supports continuous improvement initiatives. Utilizes continuous improvement and root cause analysis tools ( 5S and DMAIC)

  • Maintains a safe work environment.

  • Effectively uses process automation systems (i.e. Delta V and OSI/Pi Historian) and supporting business systems (i.e. Microsoft Dynamics/SAP/ERP Systems, Trackwise, Document Management Systems, Microsoft SharePoint etc.)


  • HS diploma, Associates Degree, or BS/BA in Biotechnology, Microbiology, Cell Biology, Chemical Engineering, Biochemistry or equivalent.

  • Requires a minimum 0-3 years of experience in a biotechnology manufacturing or laboratory environment.


  • Prior experience in a Biological Pilot Plant, cGMP Clinical or Commercial Manufacturing setting

  • Knowledge of mammalian cell culture and/or microbial fermentation processes.

  • Familiarity with Production Control Systems (i.e. DeltaV), ERP Systems (i.e. Microsoft Dynamics and/or SAP) and other business systems (Document Management Systems, LIMS, Microsoft Word, Excel, etc.)

  • Ability to follow Standard Operating Procedures and work under minimal supervision.

  • Fundamental mechanical aptitude and ability to interface with computerized systems required.

  • Demonstrated capability to work as a team member in a matrix manufacturing team.

  • Excellent oral and written communication skills.


  • Must be able to climb flights of stairs, and be standing for 1-2 hours at a time.

  • Must be able to lift up to 25lb

  • Practical knowledge of the use of Personal Protective Equipment (PPE) to handle hazardous materials throughout site


  • Ability to work off shift (Weekends) as needed; non-routine

  • Ability to work in a clean room environment

Other Job Details:

  • Last Date to Apply for Job: December 31, 2018

  • Additional Location Information: Andover, MA

  • Eligible for Employee Referral Bonus: Yes

EEO & Employment Eligibility

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